Dibal h

DIBAL is useful in organic synthesis for a variety of reductions, including converting carboxylic acids , their derivatives, and nitriles to aldehydes . DIBAL efficiently reduces α-β unsaturated esters to the corresponding allylic alcohol. [4] By contrast, LiAlH 4 reduces esters and acyl chlorides to primary alcohols , and nitriles to primary amines [use Feiser work-up procedure]. DIBAL reacts slowly with electron-poor compounds, and more quickly with electron-rich compounds. Thus, it is an electrophilic reducing agent whereas LiAlH 4 can be thought of as a nucleophilic reducing agent.

I have found this site very very helpful at many points through my journey in Org 1 and 2, but now, towards the end of org 2 I am finding it less and less useful, which seems strange since there are more and more reactions. Why are there so few reactions of carboxylic acids? carboxylic acid chemistry is the core of org 2, not to mention biochemistry. It would be really really helpful if there were more of them. Also, I think there needs to be some consistency with where reactions are placed, if they are going from a type of molecule, they should all be grouped in that grouping, or maybe have two legends so reactions can be looked up based on their reactant or product.

Dibal h

dibal h


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